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NDA 20-717 PROVIGIL® (modafinil) Tablets FDA Approved Labeling dated August 17, 2007 enantiomers do not interconvert. At steady state, total exposure to the l-isomer is approximately three times that for the d-isomer.The trough concentration (Cminss) of circulating modafinil after once daily dosing consists of 90% of the l-isomer and 10% of …Modafinil, which may be sold under brand names Modavigil, Modafin, and Nuvigil, is commonly employed in treating sleep disorders such as narcolepsy and ...…

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